Description
Technical Specifications
| Parameter | Details |
|---|---|
| Product Model | PCI-6251 |
| Manufacturer | National Instruments |
| NI Part Number | 779070-01 |
| Product Family | M Series |
| Product Type | Multifunction DAQ board |
| Host Interface | PCI |
| Analog Inputs | 16 single-ended or 8 differential |
| ADC Resolution | 16 bits |
| Maximum AI Sampling Rate | 1.25 MS/s, single channel |
| Multichannel AI Rate | 1.00 MS/s aggregate |
| Analog Input Ranges | ±0.1, ±0.2, ±0.5, ±1, ±2, ±5, ±10 V |
| Analog Outputs | 2 |
| DAC Resolution | 16 bits |
| Maximum AO Update Rate | 2.86 MS/s, single channel |
| Digital I/O | 24 lines |
| Correlated Digital I/O | 8 lines, up to 10 MHz |
| Counter/Timers | 2 × 32-bit |
| Analog Input FIFO | 4,095 samples |
| Analog Input Bandwidth | 1.7 MHz |
| Input CMRR | 100 dB, DC to 60 Hz |
| Connector | 68-pin VHDCI |
| Operating Temperature | 0°C to 55°C |
Specifications are based on NI’s M Series documentation and PCI-6251 product references. The 1.25 MS/s figure is the single-channel maximum; multichannel acquisition is limited to 1.00 MS/s aggregate.
Product Introduction
National Instruments PCI-6251 M Series DAQ Board
The National Instruments PCI-6251 is a multifunction data acquisition board designed for high-speed analog measurement and mixed-signal test applications. It provides 16-bit analog-to-digital conversion, 16 single-ended or 8 differential input channels, and two 16-bit analog outputs. Its 24 digital I/O lines and two 32-bit counter/timers extend its use to digital monitoring, pulse measurement, and signal generation.

PCI-6251
The board supports programmable input ranges from ±0.1 V to ±10 V and hardware-timed acquisition. This makes it suitable for automated test equipment, laboratory instrumentation, and industrial measurement systems built around PCI computers. Its original driver and application configuration should be checked before integrating it into a replacement computer.
Application Scenarios & Field Pitfalls
The PCI-6251 is appropriate for systems that combine analog sensor acquisition, voltage signal generation, and digital event monitoring. In automated test environments, its analog channels can collect measurement data while counter/timer and digital lines handle pulse counting, triggering, and synchronization.
Potential application areas
- Automated test equipment requiring synchronized analog acquisition and output.
- Industrial sensor monitoring and voltage measurement.
- Laboratory instrumentation and data logging.
- Pulse counting, encoder measurement, and digital event detection.
- Production test systems requiring mixed analog and digital signal handling.
Engineer checks before replacement
- Confirm the physical PCI interface. The PCI-6251 is a conventional PCI board, not the PCIe-6251. Check the host computer’s slot type before ordering.
- Verify the connector and cable. The board uses a 68-pin VHDCI connector. Confirm the existing cable, terminal block, and signal breakout arrangement.
- Check analog input configuration. The board supports 16 single-ended or 8 differential channels. Incorrect grounding or wiring configuration can introduce measurement errors.
- Observe sampling-rate limits. The 1.25 MS/s maximum applies to a single input channel. Multichannel acquisition has a 1.00 MS/s aggregate limit.
- Verify driver compatibility. Confirm that the installed NI-DAQmx version, operating system, LabVIEW version, and application software support the .
- Check analog output loading. NI specifies a ±5 mA output-current drive. Confirm the connected load does not exceed the analog output’s electrical limits.
Related Products
These NI M Series boards provide related DAQ functionality, but their channel counts, resolution, and sampling performance differ.
- PCI-6250 — Related 16-bit M Series acquisition board with 16 analog inputs. Unlike the , it does not provide the same two-channel analog output configuration.
- PCI-6254 — 16-bit DAQ board with 32 analog input channels and 1 MS/s aggregate sampling. Suitable for higher-channel-count acquisition, but not a direct channel-equivalent replacement.
- PCI-6259 — M Series board with 32 analog inputs and four analog outputs. It offers greater I/O capacity and requires a separate wiring review.
- PCI-6281 — 18-bit M Series DAQ board with 16 analog inputs and a 500 kS/s sampling rate. It provides higher ADC resolution but a lower sampling rate.
- PCIe-6251 — PCI Express version of the 6251 family. Its bus interface differs from the conventional , so it is not a mechanically interchangeable board.
- PXI-6251 — PXI-format M Series multifunction DAQ module with similar core acquisition functions. It requires a compatible PXI chassis rather than a standard PCI slot.
- USB-6251 — USB-based version of the M Series 6251 functionality. Its host interface and connection arrangement differ from the PCI board.
Procurement recommendation: The NI is associated with NI part number 779070-01. Before ordering, verify the board label, PCI interface, 68-pin connector, and cable assembly. For an existing test system, also confirm the NI-DAQmx driver version and original channel configuration.
